Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism
Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism Decreasing the dietary intake of methionine...
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Nov 11, 2022
Cellular Reprogramming, a Viable Means of Lifespan Extension
Age is the number one factor associated with the reduced function of multiple organ systems of almost every known organism. Attempts to...
Oct 21, 2022
A Bunch of Grapes a Day Might Keep the Doctor Away
It is well established that nutrition is vitally important to maintain health and to promote longevity. In addition to the macronutrients...
Oct 12, 2022
Cumulative consumption of sulfur amino acids and risk of diabetes: a prospective cohort study
Cumulative consumption of sulfur amino acids and risk of diabetes: a prospective cohort study Cross-sectional studies suggested that...
Sep 16, 2022
Key Feature of Ant Longevity Revealed
In an attempt to understand secrets of longevity, researchers are focusing on the peculiar lifespan of ants , specifically queen ants....
Aug 18, 2022
Pharmaceutical Targeting of Mitochondria to Extend Lifespan
The mitochondrion, often referred to as the powerhouse of the cell, provides a valuable resource through the production of ATP, the...
Aug 2, 2022
Cannabis-Derived Compound Extends Lifespan through Common Pro-Longevity Pathway
Cannabidiol (CBD), a non-hallucinogenic compound derived from the Cannabis sativa plant, has become a popular and effective supplement...
Jul 28, 2022
2022 Norman Orentreich Award for Young Investigator on Aging
OFAS presented the third Dr. Norman Orentreich Award for Young Investigator on Aging to Maximilian Schmid-Siegel, a Ph.D. candidate at...
Jul 25, 2022
An intermittent form of methionine restriction protects against obesity and may extend lifespan
An intermittent variation of the dietary intervention methionine restriction protects against obesity and provides additional metabolic...
Jul 19, 2022
Compound Found in Traditional Chinese Medicine Extends Lifespan
Modern science has scoured the planet for naturally-occurring compounds that might hold medicinal benefits. For example, rapamycin,...
Jun 6, 2022
Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to
A sustained state of methionine restriction (MR) dramatically extends the healthspan of several model organisms. For example,...
May 25, 2022
The Key to Getting More Mileage Out of the Brain: Change the Fluids
A recent study from Stanford University School of Medicine demonstrates the partial restoration of brain function in old mice with...
Apr 28, 2022
Cool Down, Live Longer
The Second Law of Thermodynamics dictates that heat, not resulting in work, will increase a system’s state of entropy, and very simply...
Mar 31, 2022
Turning Back the Cellular Clock
Thinking of biological aging as analogous to a clock, research has given us two distinct avenues of lifespan-extending intervention: the...
Mar 11, 2022
Weight Loss Drug Shown to Reduce Obesity and Increase Muscle Mass
In June 2021, the FDA approved semaglutide, a highly anticipated pharmaceutical treatment for obesity. This marked the first weight-loss...
Feb 23, 2022
Can We Be Immunized Against Old Age?
Vaccines have been on the mind of almost everyone for the last two years. Undoubtedly, vaccines have led to a near incalculable benefit...
Jan 28, 2022
Blood from Exercised Mice Supports the Brain Health of Sedentary Mice
Exercise has for many years been known to be among the most robust means to support a healthy and long lifespan. In a previous post, we...
Jan 28, 2022
2021 OFAS Report of Directors
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Jan 7, 2022
Erectile Dysfunction Pill Shows Promise as Alzheimer’s Disease Therapeutic
According to the CDC, an estimated 5.8 million people over age 65 suffer from Alzheimer’s disease (AD), a population predicted to triple...
Dec 16, 2021
Targeted Removal of Senescent Cells in Adipose Tissue Improves Type 2 Diabetes
Nearly half of all adults in the U.S. are considered obese, and the incidence of obesity has steadily risen over time in nearly every...
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