The role of autophagy in the regulation of yeast life span
Tyler JK, Johnson JE Ann. N. Y. Acad. Sci. 2018 Jan; PMID: 29363766 The goal of the aging field is to develop novel therapeutic...
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Dec 5, 2017
Bone marrow adipocytes.
Horowitz MC, Berry R, Holtrup B, Sebo Z, Nelson T, Fretz JA, Lindskog D, Kaplan JL, Ables GP, Rodeheffer MS, Rosen CJ. Adipocyte. 2017...
Oct 23, 2017
The integrated stress response in budding yeast lifespan extension
Postnikoff SDL, Johnson JE, Tyler JK Microb Cell 2017 Oct;4(11):368-375 PMID: 29167799 Aging is a complex, multi-factorial biological...
Oct 3, 2017
Dietary methionine restriction modulates renal response and attenuates kidney injury in mice
Cooke D, Ouattara A, Ables GP FASEB J. 2017 Oct. PMID: 28970255 Methionine restriction (MR) extends the lifespan across several species,...
Jan 17, 2017
Pleiotropic responses to methionine restriction
Ables GP, Johnson JE Exp. Gerontol. 2017 Jan; PMID: 28108330 Methionine restriction (MR) extends lifespan across different species. The...
Jan 3, 2017
Short term methionine restriction increases hepatic global DNA methylation in adult but not young ma
Mattocks DA, Mentch SJ, Shneyder J, Ables GP, Sun D, Richie JP Jr, Locasale JW, Nichenametla SN Exp Gerontol. 2017 Feb; PMID: 27940170 ...
May 17, 2016
Methionine-restricted diet increases miRNAs that can target RUNX2 expression and alters bone structu
Plummer J, Park M, Perodin F, Horowitz MC, Hens JR J. Cell. Biochem. 2016 May; PMID: 27191548 Dietary methionine restriction (MR)...
Apr 18, 2016
Methionine restriction alters bone morphology and affects osteoblast differentiation
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Jan 1, 2016
Dietary restrictions, bone density, and bone quality
Huang TH, Ables GP Ann. N. Y. Acad. Sci. 2016 Jan;1363(1):26-39 PMID: 26881697 Caloric restriction (CR), protein restriction (PR), and...
Jan 1, 2016
Methionine restriction beyond life-span extension
Ables GP, Hens JR, Nichenametla SN Ann. N. Y. Acad. Sci. 2016 Jan;1363(1):68-79 PMID: 26916321 Dietary methionine restriction (MR)...
Dec 31, 2015
Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cyc
Hens JR, Sinha I, Perodin F, Cooper T, Sinha R, Plummer J, Perrone CE, Orentreich D BMC Cancer 2016;16(1):349 PMID: 27255182 BACKGROUND:...
Oct 31, 2015
Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
Mentch SJ, Mehrmohamadi M, Huang L, Liu X, Gupta D, Mattocks D, Gόmez Padilla P, Ables G, Bamman MM, Thalacker-Mercer AE, Nichenametla...
Aug 31, 2015
Effects of methionine restriction and endurance exercise on bones of ovariectomized rats: a study of
Huang TH, Su IH, Lewis JL, Chang MS, Hsu AT, Perrone CE, Ables GP J. Appl. Physiol. 2015 Sep;119(5):517-26 PMID: 26159761 To investigate...
Jan 1, 2015
Dietary methionine restriction in mice elicits an adaptive cardiovascular response to hyperhomocyste
Ables GP, Ouattara A, Hampton TG, Cooke D, Perodin F, Augie I, Orentreich DS Sci Rep 2015;5:8886 PMID: 25744495 Dietary methionine...
Nov 30, 2014
Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice
Sinha R, Cooper TK, Rogers CJ, Sinha I, Turbitt WJ, Calcagnotto A, Perrone CE, Richie JP Prostate 2014 Dec;74(16):1663-73 PMID: 25250521 ...
Apr 30, 2014
A methionine-restricted diet and endurance exercise decrease bone mass and extrinsic strength but in
Huang TH, Lewis JL, Lin HS, Kuo LT, Mao SW, Tai YS, Chang MS, Ables GP, Perrone CE, Yang RS J. Nutr. 2014 May;144(5):621-30 PMID: 24647387...
Jan 1, 2014
The First International Mini-Symposium on Methionine Restriction and Lifespan
Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B,...
Oct 31, 2013
Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice
Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N Metab. Clin. Exp. 2013 Nov;62(11):1651-61 PMID:...
Jun 30, 2013
Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents
Perrone CE, Malloy VL, Orentreich DS, Orentreich N Exp. Gerontol. 2013 Jul;48(7):654-60 PMID: 22819757 Restriction of dietary methionine...
Jan 1, 2012
Update on pparγ and nonalcoholic Fatty liver disease
Ables GP PPAR Res 2012;2012:912351 PMID: 22966224 Nonalcoholic fatty liver disease (NAFLD) is the most common initial presentation of...
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